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Cst7em1(cre/ERT2)Fgnx
Endonuclease-mediated Allele Detail
Summary
Symbol: Cst7em1(cre/ERT2)Fgnx
Name: cystatin F (leukocystatin); endonuclease-mediated mutation 1, Florent Ginhoux
MGI ID: MGI:8395559
Synonyms: Cst7(cre/ERT2)Fgnx
Gene: Cst7  Location: Chr2:150412335-150420864 bp, + strand  Genetic Position: Chr2, 74.67 cM, cytoband G1-G3
Alliance: Cst7em1(cre/ERT2)Fgnx page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Cst7em1(cre/ERT2)Fgnx expression driven by 1 gene
 
Mutation details: 

CRISPR/Cas9 genome editing technology was used to insert a P2A-CreER cassette at the stop codon of the endogenous Cst7 locus. (J:390169)

Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cst7 (mouse)
Summary of all recombinase alleles driven by Cst7.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cst7 Mutation:  22 strains or lines available
References
Original:  J:390169 Qian J, et al., Disease-associated microglia adopt stage-specific phenotypes that regulate T cell fate and immunity in glioma. Immunity. 2026 Jul 24;
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
07/14/2026
MGI 6.24 		The Jackson Laboratory