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Grem1em3(dre/ERT2)Gpt
Endonuclease-mediated Allele Detail
Summary
Symbol: Grem1em3(dre/ERT2)Gpt
Name: gremlin 1, DAN family BMP antagonist; endonuclease-mediated mutation 3, GemPharmatech
MGI ID: MGI:8365763
Synonyms: Grem1em1Cin(P2A-DreERT2)
Gene: Grem1  Location: Chr2:113579020-113588993 bp, - strand  Genetic Position: Chr2, 57.43 cM
Alliance: Grem1em3(dre/ERT2)Gpt page
Mutation
origin
Strain of Origin:  C57BL/6JGpt
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Grem1em3(dre/ERT2)Gpt expression driven by 1 gene
 
Mutation details: 

Endonuclease-mediated mutation generated using CRISPR/Cas9 resulting in targeted insertion of P2A-DreERT2 at the endogenous locus. (J:293217)

Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Grem1 (mouse)
Summary of all recombinase alleles driven by Grem1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Grem1 Mutation:  20 strains or lines available
References
Original:  J:293217 GemPharmatech, GemPharmatech Website. 2020;
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory