Gt(ROSA)26Sortm1(CAG-dcas9/DNMT3A,-EGFP)Xsl
Targeted Allele Detail
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| Symbol: |
Gt(ROSA)26Sortm1(CAG-dcas9/DNMT3A,-EGFP)Xsl |
| Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 1, X Shawn Liu |
| MGI ID: |
MGI:8296710 |
| Synonyms: |
dCas9-Dnmt3a, LSL-dCas9-DNMT3 |
| Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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| Alliance: |
Gt(ROSA)26Sortm1(CAG-dcas9/DNMT3A,-EGFP)Xsl page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:378335
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Inserted expressed sequence, Recombinase) |
| Mutation: |
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Insertion
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Gt(ROSA)26Sortm1(CAG-dcas9/DNMT3A,-EGFP)Xsl expresses
1 gene
Knock-in expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
DNMT3A (1788) |
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Gt(ROSA)26Sortm1(CAG-dcas9/DNMT3A,-EGFP)Xsl expression driven by
1 gene
Knock-in expression driven by:
| Organism |
Driver Gene |
Note |
| chicken |
CAG |
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Mutation details: A CAG-LoxP-Stop-LoxP-dCas9/Dnmt3a-P2A-EGFP was knocked into Rosa26 locus via homologous recombination.
(J:101977, J:378335)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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CAG
(chicken)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Gt(ROSA)26Sor Mutation: |
1205 strains or lines available
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| Original: |
J:378335 Pan R, et al., Editing DNA methylation in vivo. Nat Commun. 2025 Dec 10;17(1):527 |
| All: |
2 reference(s) |
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Analysis Tools
