About   Help   FAQ
Mab21l2em1(icre/ERT2)Srin
Endonuclease-mediated Allele Detail
Summary
Symbol: Mab21l2em1(icre/ERT2)Srin
Name: mab-21-like 2; endonuclease-mediated mutation 1, Shankar Srinivas
MGI ID: MGI:8289123
Synonyms: Mab21l2-iCreERT2
Gene: Mab21l2  Location: Chr3:86453357-86455590 bp, - strand  Genetic Position: Chr3, 37.86 cM
Alliance: Mab21l2em1(icre/ERT2)Srin page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout, Recombinase)
Mutation:    Insertion
 
Mab21l2em1(icre/ERT2)Srin expression driven by 1 gene
 
Mutation details: CRISPR/Cas9 genome editing technology was used to insert a TdTomato-T2A-iCreERT2-E2A construct, in-frame and immediately downstream of the start codon sequence. (J:303268)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Mab21l2 (mouse)
Summary of all recombinase alleles driven by Mab21l2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mab21l2 Mutation:  22 strains or lines available
References
Original:  J:303268 Tyser RCV, et al., Characterization of a common progenitor pool of the epicardium and myocardium. Science. 2021 Mar 5;371(6533)
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/24/2026
MGI 6.24 		The Jackson Laboratory