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Cyp11a1em1(cre)Wans
Endonuclease-mediated Allele Detail
Summary
Symbol: Cyp11a1em1(cre)Wans
Name: cytochrome P450, family 11, subfamily a, polypeptide 1; endonuclease-mediated mutation 1, Shie Wang
MGI ID: MGI:8270881
Synonyms: Cyp11a1-Cre
Gene: Cyp11a1  Location: Chr9:57913694-57934306 bp, + strand  Genetic Position: Chr9, 31.63 cM
Alliance: Cyp11a1em1(cre)Wans page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Cyp11a1em1(cre)Wans expression driven by 1 gene
 
Mutation details: CRISPR/cas9-mediated recombination inserted an IRES-cre-wpre-pA cassette in-frame after the termination codon sites. (J:376299)
Inheritance:    Not Specified
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cyp11a1 (mouse)
Summary of all recombinase alleles driven by Cyp11a1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cyp11a1 Mutation:  42 strains or lines available
References
Original:  J:376299 Sun J, et al., Trps1 acts as a regulator of Sf-1 transcription and testosterone synthesis in mouse Leydig cells. Cell Biol Toxicol. 2023 Dec;39(6):3141-3157
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory