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Gene Expression Data
Assay Details
Assay
Reference: J:366215 Rudat C, et al., PPARG contributes to urothelial integrity in the murine ureter by activating the expression of Shh and superficial cell-specific genes. Development. 2025 Apr 15;152(8)
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8268808
Gene symbol: Trp63
Gene name: transformation related protein 63
Antibody: Anti-deltaNp63 (619001)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2D deltaNP63 control: postnatal day 40; Ppargtm2Rev/? (more )
Structure Level Pattern Image Note
TS28: basal cell layer of ureter Present 2D deltaNP63 control Expression in B cells and I cells.
TS28: intermediate cell layer of ureter Present 2D deltaNP63 control Expression in B cells and I cells.

Specimen 2D deltaNP63 cKO: postnatal day 40; Ppargtm2Rev/Ppargtm2Rev, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: basal cell layer of ureter Present 2D deltaNP63 cKO Expression restricted to basal layer.

Specimen 3C deltaNP63 E14.5 control: embryonic day 14.5; Ppargtm2Rev/? (more )
Structure Level Pattern Image Note
TS22: urothelium of ureter Present 3C DNP53 E14.5 control Expression started at E14.5.

Specimen 3C deltaNP63 E14.5 cKO: embryonic day 14.5; Ppargtm2Rev/Ppargtm2Rev, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: urothelium of ureter Present 3C DNP53 E14.5 cKO Expression normally activated at E14.5

Specimen 3C deltaNP63 E16.5 control: embryonic day 16.5; Ppargtm2Rev/? (more )
Structure Level Pattern Image Note
TS24: basal cell layer of ureter Strong 3C DNP53 E16.5 control High levels of expression in B cells.
TS24: intermediate cell layer of ureter Weak 3C DNP53 E16.5 control Lower levels of expression in I cells.

Specimen 3C deltaNP63 E16.5 cKO: embryonic day 16.5; Ppargtm2Rev/Ppargtm2Rev, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: basal cell layer of ureter Present 3C DNP53 E16.5 cKO Expression restricted to B cell layer.

Specimen 3C deltaNP63 E18.5 control: embryonic day 18.5; Ppargtm2Rev/? (more )
Structure Level Pattern Image Note
TS26: basal cell layer of ureter Strong 3C DNP53 E18.5 control High levels of expression in B cells.
TS26: intermediate cell layer of ureter Weak 3C DNP53 E18.5 control Lower levels of expression in I cells.

Specimen 3C deltaNP63 E18.5 cKO: embryonic day 18.5; Ppargtm2Rev/Ppargtm2Rev, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: basal cell layer of ureter Present 3C DNP53 E18.5 cKO Expression restricted to B cell layer.

Specimen 3C deltaNP63 P7 control: postnatal day 7; Ppargtm2Rev/? (more )
Structure Level Pattern Image Note
TS28: basal cell layer of ureter Strong 3C DNP53 P7 control High levels of expression in B cells.
TS28: intermediate cell layer of ureter Weak 3C DNP53 P7 control Lower levels of expression in I cells.

Specimen 3C deltaNP63 P7 cKO: postnatal day 7; Ppargtm2Rev/Ppargtm2Rev, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: basal cell layer of ureter Present 3C DNP53 P7 cKO Expression restricted to B cell layer.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/06/2026
MGI 6.29
The Jackson Laboratory