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Slco2b1tm2.1(icre,CD2)Ciphe
Targeted Allele Detail
Summary
Symbol: Slco2b1tm2.1(icre,CD2)Ciphe
Name: solute carrier organic anion transporter family, member 2b1; targeted mutation 2.1, Centre d'ImmunoPhenomique
MGI ID: MGI:8268637
Synonyms: Slco2b1hCD2, Slco2b1-IRES-iCre-P2A-hCD2t, Slco2b1tm2Ciphe
Gene: Slco2b1  Location: Chr7:99307011-99360547 bp, - strand  Genetic Position: Chr7, 54.11 cM
Alliance: Slco2b1tm2.1(icre,CD2)Ciphe page
IMPC: Slco2b1 gene page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:372683
Parent Cell Line:  JM8.F6 (ES Cell)
Strain of Origin:  C57BL/6N
Project Collection: KOMP-CSD
Mutation
description
Allele Type:    Targeted (Humanized sequence, Recombinase)
Mutation:    Insertion
 
Slco2b1tm2.1(icre,CD2)Ciphe expresses 1 gene
 
Slco2b1tm2.1(icre,CD2)Ciphe expression driven by 1 gene
 
Mutation detailsAn IRES-icre-P2a-human CD2 cassette was inserted into the 3' untranslated region, 30 bp downstream of the stop codon, via homologous recombination. An FRT-flanked neo cassette was removed after selection. (J:372683)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Slco2b1 (mouse)
Summary of all recombinase alleles driven by Slco2b1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slco2b1 Mutation:  36 strains or lines available
References
Original:  J:372683 Pervizou D, et al., Characterization of the immune landscape in healthy mouse prostate and during prostate cancer progression. Oncoimmunology. 2025 Dec;14(1):2562220
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory