Slco2b1tm2.1(icre,CD2)Ciphe
Targeted Allele Detail
|
|
| Symbol: |
Slco2b1tm2.1(icre,CD2)Ciphe |
| Name: |
solute carrier organic anion transporter family, member 2b1; targeted mutation 2.1, Centre d'ImmunoPhenomique |
| MGI ID: |
MGI:8268637 |
| Synonyms: |
Slco2b1hCD2, Slco2b1-IRES-iCre-P2A-hCD2t, Slco2b1tm2Ciphe |
| Gene: |
Slco2b1 Location: Chr7:99307011-99360547 bp, - strand Genetic Position: Chr7, 54.11 cM
|
| Alliance: |
Slco2b1tm2.1(icre,CD2)Ciphe page
|
| IMPC: |
Slco2b1 gene page |
|
| Germline Transmission: |
Earliest citation of germline transmission:
J:372683
|
| Parent Cell Line: |
JM8.F6 (ES Cell)
|
| Strain of Origin: |
C57BL/6N
|
| Project Collection: |
KOMP-CSD
|
|
| Allele Type: |
|
Targeted (Humanized sequence, Recombinase) |
| Mutation: |
|
Insertion
|
| |
|
Slco2b1tm2.1(icre,CD2)Ciphe expresses
1 gene
Knock-in expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
CD2 (914) |
|
|
|
| |
|
Slco2b1tm2.1(icre,CD2)Ciphe expression driven by
1 gene
Knock-in expression driven by:
|
| |
|
Mutation details: An IRES-icre-P2a-human CD2 cassette was inserted into the 3' untranslated region, 30 bp downstream of the stop codon, via homologous recombination. An FRT-flanked neo cassette was removed after selection.
(J:372683)
|
|
|
|
Activity: |
 Tissue activity of this recombinase allele
|
|
Driver:
|
Slco2b1
(mouse)
|
| |
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
| Carrying any Slco2b1 Mutation: |
36 strains or lines available
|
|
| Original: |
J:372683 Pervizou D, et al., Characterization of the immune landscape in healthy mouse prostate and during prostate cancer progression. Oncoimmunology. 2025 Dec;14(1):2562220 |
| All: |
1 reference(s) |
|