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Oprm1em1(cre/ERT2)Chel
Endonuclease-mediated Allele Detail
Summary
Symbol: Oprm1em1(cre/ERT2)Chel
Name: opioid receptor, mu 1; endonuclease-mediated mutation 1, Longzhen Cheng
MGI ID: MGI:8268627
Synonyms: OprmecreER
Gene: Oprm1  Location: Chr10:6708593-6988209 bp, + strand  Genetic Position: Chr10, 1.85 cM, cytoband A2
Alliance: Oprm1em1(cre/ERT2)Chel page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Oprm1em1(cre/ERT2)Chel expression driven by 1 gene
    CRISPR/cas9-mediated recombination inserted a P2A-cre/ERT2 cassette in front of the stop codon. (J:375289)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Oprm1 (mouse)
Summary of all recombinase alleles driven by Oprm1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Oprm1 Mutation:  55 strains or lines available
References
Original:  J:375289 Du F, et al., Targeting Peripheral mu-opioid Receptors or mu-opioid Receptor-Expressing Neurons Does not Prevent Morphine-induced Mechanical Allodynia and Anti-allodynic Tolerance. Neurosci Bull. 2023 Aug;39(8):1210-1228
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory