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Il1bem1(cre/ERT2)Quan
Endonuclease-mediated Allele Detail
Summary
Symbol: Il1bem1(cre/ERT2)Quan
Name: interleukin 1 beta; endonuclease-mediated mutation 1, Ning Quan
MGI ID: MGI:8268524
Synonyms: IL-1beta-IRES-Cre-ERT2
Gene: Il1b  Location: Chr2:129206490-129213059 bp, - strand  Genetic Position: Chr2, 62.97 cM, cytoband F
Alliance: Il1bem1(cre/ERT2)Quan page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Il1bem1(cre/ERT2)Quan expression driven by 1 gene
 
Mutation details: CRISPR/Cas9 genome editing technology was used to insert an IRES2-iCreERT2 into the 3 UTR of exon 7 after the stop codon. (J:375900)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Il1b (mouse)
Summary of all recombinase alleles driven by Il1b.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Il1b Mutation:  21 strains or lines available
References
Original:  J:375900 Nemeth DP, et al., Temporally-regulated genetic access to IL-1beta-expressing cellular networks in homeostasis and following peripheral or central immune stimuli. Brain Behav Immun. 2026 Jan;131:106177
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory