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Smoc2em1(cre/ERT2)Hza
Endonuclease-mediated Allele Detail
Summary
Symbol: Smoc2em1(cre/ERT2)Hza
Name: SPARC related modular calcium binding 2; endonuclease-mediated mutation 1, Hu Zhao
MGI ID: MGI:8268471
Synonyms: Smoc2-CreERT2
Gene: Smoc2  Location: Chr17:14499768-14625052 bp, + strand  Genetic Position: Chr17, 8.95 cM, cytoband A2
Alliance: Smoc2em1(cre/ERT2)Hza page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Smoc2em1(cre/ERT2)Hza expression driven by 1 gene
    CRISPR/cas9-mediated recombination inserted a P2A-cre/ERT2 cassette near the stop codon of the gene. (J:375771)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Smoc2 (mouse)
Summary of all recombinase alleles driven by Smoc2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Smoc2 Mutation:  25 strains or lines available
References
Original:  J:375771 Chen Z, et al., Autocrine ECM molecules establish MSC quiescence during incisor development by disrupting WNT ligand trafficking process. Nat Commun. 2025 Nov 27;16(1):10676
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory