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Il2rbem1(cre)Zdo
Endonuclease-mediated Allele Detail
Summary
Symbol: Il2rbem1(cre)Zdo
Name: interleukin 2 receptor, beta chain; endonuclease-mediated mutation 1, Zhongjun Dong
MGI ID: MGI:8266591
Synonyms: CD122Cre
Gene: Il2rb  Location: Chr15:78363456-78379471 bp, - strand  Genetic Position: Chr15, 37.52 cM, cytoband E
Alliance: Il2rbem1(cre)Zdo page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Il2rbem1(cre)Zdo expression driven by 1 gene
 
Mutation details: CRISPR/cas9 mediated recombination inserted an IRES-cre-SV40 polyA cassette was inserted in the 3' end of the gene. (J:374697)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Il2rb (mouse)
Summary of all recombinase alleles driven by Il2rb.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Il2rb Mutation:  34 strains or lines available
References
Original:  J:374697 Chen S, et al., Dual Activity of Type III PI3K Kinase Vps34 is Critical for NK Cell Development and Senescence. Adv Sci (Weinh). 2024 Jun;11(21):e2309315
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory