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Chrna2em1(cre)Wuj
Endonuclease-mediated Allele Detail
Summary
Symbol: Chrna2em1(cre)Wuj
Name: cholinergic receptor nicotinic alpha 2 subunit; endonuclease-mediated mutation 1, Jun Wu
MGI ID: MGI:8262991
Synonyms: Chrna2Endo-Cre
Gene: Chrna2  Location: Chr14:66372488-66390397 bp, + strand  Genetic Position: Chr14, 34.36 cM
Alliance: Chrna2em1(cre)Wuj page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Chrna2em1(cre)Wuj expression driven by 1 gene
    CRISPR/cas9-mediated recombination inserted an HA-P2A-Cre cassette near the stop codon in exon 7. (J:374720)
Inheritance:    Not Specified
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Chrna2 (mouse)
Summary of all recombinase alleles driven by Chrna2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Chrna2 Mutation:  34 strains or lines available
References
Original:  J:374720 Zhu K, et al., Chrna2-driven CRE Is Expressed in Beige Adipocytes. Endocrinology. 2024 Nov 26;166(1)
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory