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Krt16em1(cre/ERT2)Smoc
Endonuclease-mediated Allele Detail
Summary
Symbol: Krt16em1(cre/ERT2)Smoc
Name: keratin 16; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
MGI ID: MGI:8261415
Synonyms: K16CreER, Krt16-2A-CreERT2, Krt16em1(2A-CreERT2-WPRE-pA)Smoc
Gene: Krt16  Location: Chr11:100136917-100139728 bp, - strand  Genetic Position: Chr11, 63.44 cM
Alliance: Krt16em1(cre/ERT2)Smoc page
Mutation
origin
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Krt16em1(cre/ERT2)Smoc expression driven by 1 gene
    CRISPR/cas9-mediated recombination inserted a 2A-CreERT2-WPRE-pA cassette into the stop codon. (J:279175)
Inheritance:    Not Specified
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Krt16 (mouse)
Summary of all recombinase alleles driven by Krt16.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Krt16 Mutation:  29 strains or lines available
References
Original:  J:366754 Qin Z, et al., Co-targeting BMI1 and MYC to eliminate cancer stem cells in squamous cell carcinoma. Cell Rep Med. 2025 Apr 8;:102077
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory