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Tfap2bem1(cre/ERT2)Ychai
Endonuclease-mediated Allele Detail
Summary
Symbol: Tfap2bem1(cre/ERT2)Ychai
Name: transcription factor AP-2 beta; endonuclease-mediated mutation 1, Yang Chai
MGI ID: MGI:8261411
Synonyms: Tfap2b-CreERT2
Gene: Tfap2b  Location: Chr1:19279138-19308800 bp, + strand  Genetic Position: Chr1, 6.19 cM, cytoband A2-A4
Alliance: Tfap2bem1(cre/ERT2)Ychai page
Mutation
origin
Strain of Origin:  B6D2F1
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tfap2bem1(cre/ERT2)Ychai expression driven by 1 gene
 
Mutation details: CRISPR/cas9-mediated recombination inserted a 2A-cre/ERT2 cassette in exon 7 at the end of the coding region. (J:366831)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tfap2b (mouse)
Summary of all recombinase alleles driven by Tfap2b.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tfap2b Mutation:  32 strains or lines available
References
Original:  J:366831 Zhang M, et al., Generation of tamoxifen-inducible Tfap2b-CreER(T2) mice using CRISPR-Cas9. Genesis. 2024 Feb;62(1):e23582
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory