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Grprtm1(flp)Felj
Targeted Allele Detail
Summary
Symbol: Grprtm1(flp)Felj
Name: gastrin releasing peptide receptor; targeted mutation 1, Jack L Feldman
MGI ID: MGI:8261368
Synonyms: GrprFlp
Gene: Grpr  Location: ChrX:162296900-162332673 bp, - strand  Genetic Position: ChrX, 75.63 cM
Alliance: Grprtm1(flp)Felj page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:369761
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutations:    Insertion, Intragenic deletion
 
Grprtm1(flp)Felj expression driven by 1 gene
 
Mutation details: The stop codon in exon 3 was replaced with a flp cassette and an FRT-flanked neo cassette was inserted via homologous recombination. Flp-mediated recombination removed the neo cassette. (J:369761)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Grpr (mouse)
Summary of all recombinase alleles driven by Grpr.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Grpr Mutation:  16 strains or lines available
References
Original:  J:369761 Cui Y, et al., Sigh generation in preBotzinger complex. Elife. 2025 Jun 24;13
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory