Sox9tm1.1(rtTA,flpo)Que
Targeted Allele Detail
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| Symbol: |
Sox9tm1.1(rtTA,flpo)Que |
| Name: |
SRY (sex determining region Y)-box 9; targeted mutation 1.1, Jianwen Que |
| MGI ID: |
MGI:8261228 |
| Synonyms: |
Sox9flippase, Sox9Flp |
| Gene: |
Sox9 Location: Chr11:112673050-112678586 bp, + strand Genetic Position: Chr11, 77.27 cM
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| Alliance: |
Sox9tm1.1(rtTA,flpo)Que page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:366013
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Conditional ready, Recombinase, Transactivator) |
| Mutation: |
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Insertion
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Sox9tm1.1(rtTA,flpo)Que expression driven by
1 gene
Knock-in expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Sox9 (MGI:98371) |
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Mutation details: A construct containing a loxp(66)-rtTA-T2A-flpo-IRES-loxp(71) cassette and an FRT-flanked neo cassette was inserted before the stop codon. Flp-mediated recombination removed the neo cassette. Flp is only expressed when the construct is inverted by cre-mediated recombination.
(J:366013)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Sox9
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Sox9 Mutation: |
33 strains or lines available
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| Original: |
J:366013 Chen Q, et al., SOX9 Modulates the Transformation of Gastric Stem Cells Through Biased Symmetric Cell Division. Gastroenterology. 2023 Jun;164(7):1119-1136.e12 |
| All: |
1 reference(s) |
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Analysis Tools
