About   Help   FAQ
Sspoem1(icre)Wopg
Endonuclease-mediated Allele Detail
Summary
Symbol: Sspoem1(icre)Wopg
Name: SCO-spondin; endonuclease-mediated mutation 1, Woo-ping Ge
MGI ID: MGI:8261036
Synonyms: Sspo-Cre
Gene: Sspo  Location: Chr6:48425163-48478184 bp, + strand  Genetic Position: Chr6, 23.42 cM
Alliance: Sspoem1(icre)Wopg page
Mutation
origin
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Sspoem1(icre)Wopg expression driven by 1 gene
    CRISPR/cas9-mediated recombination inserted an icre-WPRE-pA cassette adjacent to the start codon. (J:374541)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Sspo (mouse)
Summary of all recombinase alleles driven by Sspo.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sspo Mutation:  224 strains or lines available
References
Original:  J:374541 Zhang T, et al., The subcommissural organ regulates brain development via secreted peptides. Nat Neurosci. 2024 Jun;27(6):1103-1115
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/07/2025
MGI 6.24 		The Jackson Laboratory