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Npbwr1tm1.1(icre)Stak
Targeted Allele Detail
Summary
Symbol: Npbwr1tm1.1(icre)Stak
Name: neuropeptides B/W receptor 1; targeted mutation 1.1, Takeshi Sakurai
MGI ID: MGI:8260943
Synonyms: Npbwr1Cre
Gene: Npbwr1  Location: Chr1:5983926-5987617 bp, - strand  Genetic Position: Chr1, 1.89 cM, cytoband A1
Alliance: Npbwr1tm1.1(icre)Stak page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:364869
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutations:    Insertion, Intragenic deletion
 
Npbwr1tm1.1(icre)Stak expression driven by 1 gene
 
Mutation details: An icre-pA cassette and and FRT-flanked pgk/gb2-neo cassette were inserted into the gene replacing a 355 bp region. Flp-mediated recombination removed the neo cassette. (J:364869)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Npbwr1 (mouse)
Summary of all recombinase alleles driven by Npbwr1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Npbwr1 Mutation:  21 strains or lines available
References
Original:  J:364869 Soya S, et al., Central amygdala NPBWR1 neurons facilitate social novelty seeking and new social interactions. Sci Adv. 2025 Jan 17;11(3):eadn1335
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory