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Vil1em1(flp)Xug
Endonuclease-mediated Allele Detail
Summary
Symbol: Vil1em1(flp)Xug
Name: villin 1; endonuclease-mediated mutation 1, Geyang Xu
MGI ID: MGI:8260933
Synonyms: Vil1FLP
Gene: Vil1  Location: Chr1:74448543-74474719 bp, + strand  Genetic Position: Chr1, 38.54 cM, cytoband C5
Alliance: Vil1em1(flp)Xug page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Vil1em1(flp)Xug expression driven by 1 gene
 
Mutation details: CRISPR/cas9-mediated recombination inserted a 2A-flp-WPRE-pA cassette into the stop codon of exon 20. (J:364895)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Vil1 (mouse)
Summary of all recombinase alleles driven by Vil1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Vil1 Mutation:  50 strains or lines available
References
Original:  J:364895 Huang Y, et al., Mechano-regulation of GLP-1 production by Piezo1 in intestinal L cells. Elife. 2024 Nov 7;13
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
10/07/2025
MGI 6.24 		The Jackson Laboratory