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Gene Expression Data
Assay Details
Assay
Reference: J:276459 Lahrouchi N, et al., Homozygous frameshift mutations in FAT1 cause a syndrome characterized by colobomatous-microphthalmia, ptosis, nephropathy and syndactyly. Nat Commun. 2019 Mar 12;10(1):1180
Assay type: RNA in situ
MGI Accession ID: MGI:8260930
Gene symbol: Fat1
Gene name: FAT atypical cadherin 1
Probe: Fat1 probe
Probe preparation: Antisense RNA
Results
Specimen 2a: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: optic cup Present 2a
TS17: optic stalk Present Regionally restricted 2a Expressed in the edges of the optic fissure apposing the optic cup.
TS17: eye mesenchyme Present Regionally restricted 2a Expressed in the perioptic mesenchyme.
TS17: lens vesicle Present 2a
Specimen 2b: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: neural retina Present 2b More highly expressed in the nasal than in the temporal portion.
TS19: lens vesicle Present 2b
TS19: perioptic mesenchyme Present 2b
TS19: retina Present 2b
TS19: optic fissure Present Regionally restricted 2b Expressed in the edges apposing the optic cup.
Specimen 2c: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lens vesicle Present 2c
TS20: neural retina Present 2c
TS20: perioptic mesenchyme Present 2c
TS20: optic fissure Present Regionally restricted 2c Expressed in the edges apposing the optic cup.
Specimen 2d: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: eye mesenchyme Present Regionally restricted 2d Expressed in the perioptic mesenchyme. Expression was elevated in the ventral compartment as compared to the dorsal compartment.
TS17: lens vesicle Present 2d
TS17: neural retina Present 2d
TS17: optic cup Present 2d
Specimen 2e: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: perioptic mesenchyme Present 2e Expression was elevated in the ventral compartment as compared to the dorsal compartment.
TS19: lens vesicle Present 2e
TS19: optic fissure Present 2e
TS19: retina Present 2e
Specimen 2f: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: perioptic mesenchyme Present 2f Expression was elevated in the ventral compartment as compared to the dorsal compartment.
TS20: lens vesicle Present 2f
TS20: optic fissure Present 2f
TS20: retina Present 2f
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/06/2026
MGI 6.29 		The Jackson Laboratory