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Il17ratm1.1(icre)Gcho
Targeted Allele Detail
Summary
Symbol: Il17ratm1.1(icre)Gcho
Name: interleukin 17 receptor A; targeted mutation 1.1, Gloria Choi
MGI ID: MGI:8259624
Synonyms: Il-17ra-Cre
Gene: Il17ra  Location: Chr6:120440143-120460692 bp, + strand  Genetic Position: Chr6, 56.95 cM
Alliance: Il17ratm1.1(icre)Gcho page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:367654
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Il17ratm1.1(icre)Gcho expression driven by 1 gene
 
Mutation details: A neo caseete was inserted in intron 12 and an IRES-icre was inserted in exon 13 via homologous recombination. The neo cassette was then removed. (J:367654)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Il17ra (mouse)
Summary of all recombinase alleles driven by Il17ra.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Il17ra Mutation:  47 strains or lines available
References
Original:  J:367654 Lee B, et al., Inflammatory and anti-inflammatory cytokines bidirectionally modulate amygdala circuits regulating anxiety. Cell. 2025 Apr 17;188(8):2190-2202.e15
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory