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Muc6em1(cre/ERT2)Guv
Endonuclease-mediated Allele Detail
Summary
Symbol: Muc6em1(cre/ERT2)Guv
Name: mucin 6, gastric; endonuclease-mediated mutation 1, Vikas Gupta
MGI ID: MGI:8257777
Synonyms: Muc6:CreERT2, Muc6-IRES-CreERT2
Gene: Muc6  Location: Chr7:141213373-141241641 bp, - strand  Genetic Position: Chr7, 87.03 cM, cytoband F5
Alliance: Muc6em1(cre/ERT2)Guv page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, No functional change, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Muc6em1(cre/ERT2)Guv expression driven by 1 gene
    CRISPR/cas9 mediated recombination inserted an IRES-cre/ERT2 cassette in the 3' untranslated region. (J:342981)
Inheritance:    Not Specified
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Muc6 (mouse)
Summary of all recombinase alleles driven by Muc6.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Muc6 Mutation:  159 strains or lines available
References
Original:  J:342981 Singh S, et al., Heterogeneous murine peribiliary glands orchestrate compartmentalized epithelial renewal. Dev Cell. 2023 Oct 23;
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
10/07/2025
MGI 6.24 		The Jackson Laboratory