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Plin1tm1.1(cre/ERT2)Dinl
Targeted Allele Detail
Summary
Symbol: Plin1tm1.1(cre/ERT2)Dinl
Name: perilipin 1; targeted mutation 1.1, Lei Ding
MGI ID: MGI:8257771
Synonyms: Plin1creER
Gene: Plin1  Location: Chr7:79370912-79382652 bp, - strand  Genetic Position: Chr7, 45.11 cM
Alliance: Plin1tm1.1(cre/ERT2)Dinl page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:342688
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutations:    Insertion, Intragenic deletion
 
Plin1tm1.1(cre/ERT2)Dinl expression driven by 1 gene
 
Mutation details: A P2A-cre/ERT2 cassette and FRT-flanked neo cassette were inserted downstream of the coding region in exon 9 via homologous recombination. Flp-mediated recombination removed the neo cassette. (J:342688)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Plin1 (mouse)
Summary of all recombinase alleles driven by Plin1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Plin1 Mutation:  30 strains or lines available
Notes
Generated in FL19 ES cells on a C57BL/6 background
References
Original:  J:342688 Hirakawa H, et al., Cellular plasticity of the bone marrow niche promotes hematopoietic stem cell regeneration. Nat Genet. 2023 Nov;55(11):1941-1952
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory