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Rbfox3em1(icre)Murk
Endonuclease-mediated Allele Detail
Summary
Symbol: Rbfox3em1(icre)Murk
Name: RNA binding protein, fox-1 homolog (C. elegans) 3; endonuclease mediated mutation 1, Kazuya Murata
MGI ID: MGI:8257685
Synonyms: Rbfox3em1(IRES-iCre)Murk
Gene: Rbfox3  Location: Chr11:118380588-118802423 bp, - strand  Genetic Position: Chr11, 83.22 cM
Alliance: Rbfox3em1(icre)Murk page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Rbfox3em1(icre)Murk expression driven by 1 gene
 
Mutation details: CRISPR/Cas9 genome editing technology was used to insert an IRES-nuclear localization signal (NLS)-iCre-rabbit globin poly A signal (rGpA) sequence into 3 UTR of the gene. (J:373410)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Rbfox3 (mouse)
Summary of all recombinase alleles driven by Rbfox3.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rbfox3 Mutation:  20 strains or lines available
References
Original:  J:373410 Nishino S, et al., Characterization of the Rbfox3-IRES-iCre knock-in mouse: Revealing gene recombination activity in neural and non-neural peripheral tissues. FASEB Bioadv. 2025 Apr;7(4):e70003
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory