About   Help   FAQ
Prrx1tm1.1(icre)Bcgen
Targeted Allele Detail
Summary
Symbol: Prrx1tm1.1(icre)Bcgen
Name: paired related homeobox 1; targeted mutation 1.1, Biocytogen LLC
MGI ID: MGI:8257684
Synonyms: Prrx1-Cre, Prrx1iCre, Prrx1tm1(icre)Bcgen
Gene: Prrx1  Location: Chr1:163072688-163141279 bp, - strand  Genetic Position: Chr1, 70.53 cM
Alliance: Prrx1tm1.1(icre)Bcgen page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:342646
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout, Recombinase)
Mutation:    Insertion
 
Prrx1tm1.1(icre)Bcgen expression driven by 1 gene
 
Mutation details: An F2A-iCre sequence cassette and FRT flanked neo cassette were placed between the coding sequence of exon 1 and 5'UTR via homologous recombination. Flp-mediated recombination removed the neo cassette. (J:308681, J:342646)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Prrx1 (mouse)
Summary of all recombinase alleles driven by Prrx1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prrx1 Mutation:  31 strains or lines available
References
Original:  J:342646 Liu H, et al., Prrx1 marks stem cells for bone, white adipose tissue and dermis in adult mice. Nat Genet. 2022 Dec;54(12):1946-1958
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory