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Prdm1tm1.1(cre/ERT2)Kuro
Targeted Allele Detail
Summary
Symbol: Prdm1tm1.1(cre/ERT2)Kuro
Name: PR domain containing 1, with ZNF domain; targeted mutation 1.1, Tomohiro Kurosaki
MGI ID: MGI:8257624
Synonyms: Blimp1-CreERT2
Gene: Prdm1  Location: Chr10:44313173-44404497 bp, - strand  Genetic Position: Chr10, 23.24 cM
Alliance: Prdm1tm1.1(cre/ERT2)Kuro page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:373880
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Mutation:    Insertion
 
Prdm1tm1.1(cre/ERT2)Kuro expression driven by 1 gene
 
Mutation details: A construct containing a cre/ERT2-pA cassette and an FRT-flanked neo cassette was inserted into exon 1 just downstream from the translation start site. Flp-mediated recombination removed the neo cassette. (J:373880)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Prdm1 (mouse)
Summary of all recombinase alleles driven by Prdm1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prdm1 Mutation:  69 strains or lines available
References
Original:  J:373880 Koike T, et al., Progressive differentiation toward the long-lived plasma cell compartment in the bone marrow. J Exp Med. 2023 Feb 6;220(2)
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
10/07/2025
MGI 6.24 		The Jackson Laboratory