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Aldh1l1tm1(cre)Yono
Targeted Allele Detail
Summary
Symbol: Aldh1l1tm1(cre)Yono
Name: aldehyde dehydrogenase 1 family, member L1; targeted mutation 1.1, Yuichi Ono
MGI ID: MGI:8257003
Synonyms: Aldh1l1-IRES- Cre
Gene: Aldh1l1  Location: Chr6:90527751-90576153 bp, + strand  Genetic Position: Chr6, 40.16 cM
Alliance: Aldh1l1tm1(cre)Yono page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:371490
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Aldh1l1tm1(cre)Yono expression driven by 1 gene
 
Mutation details: An IRES-cre cassette and VloxP-flanked HSV TK-neo cassette were inserted immediately 3' of the stop codon. The neo cassette was removed by Vcre mediate recombination. (J:371490)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Aldh1l1 (mouse)
Summary of all recombinase alleles driven by Aldh1l1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Aldh1l1 Mutation:  62 strains or lines available
Notes
Targeting was done in B6J- S1UTR ES cells
References
Original:  J:371490 Izumi Y, et al., Generation of Astrocyte-Selective Cre Driver Lines With Distinct Onsets of Recombination Activity During Development. Genesis. 2025 Oct;63(5):e70025
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/07/2025
MGI 6.24 		The Jackson Laboratory