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Gas1em1(cre/ERT2)Zhya
Endonuclease-mediated Allele Detail
Summary
Symbol: Gas1em1(cre/ERT2)Zhya
Name: growth arrest specific 1; endonuclease-mediated mutation 1, Yan Zhang
MGI ID: MGI:8254782
Synonyms: Gas1 CreER KI
Gene: Gas1  Location: Chr13:60322219-60325179 bp, - strand  Genetic Position: Chr13, 31.92 cM, cytoband B3-C2
Alliance: Gas1em1(cre/ERT2)Zhya page
Mutation
origin
Strain of Origin:  C57BL/6JCya
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Gas1em1(cre/ERT2)Zhya expression driven by 1 gene
 
Mutation details: CRISPR/cas9-mediated recombination inserted a cre/ERT2 gene, WPRE sequence, and bGH-pA sequence into exon 1 just before the coding sequence. (J:369013)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gas1 (mouse)
Summary of all recombinase alleles driven by Gas1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gas1 Mutation:  16 strains or lines available
References
Original:  J:369013 Ding C, et al., Gas1-high quiescent neural stem cells are multipotent and produce oligodendrocytes during aging and after demyelinating injury. PLoS Biol. 2025 Apr;23(4):e3003100
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory