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Tnnem1(cre/ERT2)Wanw
Endonuclease-mediated Allele Detail
Summary
Symbol: Tnnem1(cre/ERT2)Wanw
Name: tenascin N; endonuclease-mediated mutation 1, Wei Wang
MGI ID: MGI:8253326
Synonyms: Tnn-P2A-CreERT2
Gene: Tnn  Location: Chr1:159912599-159981150 bp, - strand  Genetic Position: Chr1, 69.4 cM
Alliance: Tnnem1(cre/ERT2)Wanw page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Mutation:    Insertion
 
Tnnem1(cre/ERT2)Wanw expression driven by 1 gene
 
Mutation details: CRISPR/cas9-mediated recombination inserted a P2A-cre/ERT2 cassette in exon 22 at the end of the coding region. (J:370536)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tnn (mouse)
Summary of all recombinase alleles driven by Tnn.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tnn Mutation:  91 strains or lines available
References
Original:  J:370536 Lin W, et al., Reactivation of mammalian regeneration by turning on an evolutionarily disabled genetic switch. Science. 2025 Jun 26;388(6754):eadp0176
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory