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Klhl14em1(icre)Sahv
Endonuclease-mediated Allele Detail
Summary
Symbol: Klhl14em1(icre)Sahv
Name: kelch-like 14; endonuclease-mediated mutation 1, Vibhu Sahni
MGI ID: MGI:8253316
Synonyms: Klhl14-Cre
Gene: Klhl14  Location: Chr18:21683434-21787775 bp, - strand  Genetic Position: Chr18, 11.96 cM
Alliance: Klhl14em1(icre)Sahv page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Epitope tag, Recombinase)
Mutation:    Insertion
 
Klhl14em1(icre)Sahv expression driven by 1 gene
 
Mutation details: A construct containing 3xHA tags, T2A sequence, and improved cre sequence was inserted at the C-terminus via CRISPR/cas9 mediated recombination. (J:372019)
Inheritance:    Not Specified
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Klhl14 (mouse)
Summary of all recombinase alleles driven by Klhl14.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Klhl14 Mutation:  31 strains or lines available
References
Original:  J:372019 Lustig J, et al., Selective Targeting of a Defined Subpopulation of Corticospinal Neurons Using a Novel Klhl14-Cre Mouse Line Enables Molecular and Anatomical Investigations through Development into Maturity. eNeuro. 2025 Sep;12(9):ENEURO.0589-24.2025
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory