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Lcn2tm1.1(cre/ERT2)Ricm
Targeted Allele Detail
Summary
Symbol: Lcn2tm1.1(cre/ERT2)Ricm
Name: lipocalin 2; targeted mutation 1.1, Martin M Riccomagno
MGI ID: MGI:8253311
Synonyms: Lcn2CreERT2
Gene: Lcn2  Location: Chr2:32274649-32277751 bp, - strand  Genetic Position: Chr2, 22.09 cM, cytoband A3
Alliance: Lcn2tm1.1(cre/ERT2)Ricm page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:352374
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Mutation:    Insertion
 
Lcn2tm1.1(cre/ERT2)Ricm expression driven by 1 gene
 
Mutation detailsA cre/ERT2-P2A cassette was inserted between the promoter and 5' untranslated region and an FRT-flanked neo cassette was inserted downstream of the cre cassette via homologous recombination. Flp-mediated recombination removed the neo cassette. (J:352374)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Lcn2 (mouse)
Summary of all recombinase alleles driven by Lcn2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lcn2 Mutation:  30 strains or lines available
References
Original:  J:352374 Agnew-Svoboda W, et al., A genetic tool for the longitudinal study of a subset of post-inflammatory reactive astrocytes. Cell Rep Methods. 2022 Aug 22;2(8):100276
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/07/2025
MGI 6.24
The Jackson Laboratory