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Tmem119em1(cre/ERT2)Cya
Endonuclease-mediated Allele Detail
Summary
Symbol: Tmem119em1(cre/ERT2)Cya
Name: transmembrane protein 119; endonuclease-mediated mutation 1, Cyagen Biosciences
MGI ID: MGI:8253308
Synonyms: Tmem119-2A-CreERT2
Gene: Tmem119  Location: Chr5:113931790-113938457 bp, - strand  Genetic Position: Chr5, 55.55 cM
Alliance: Tmem119em1(cre/ERT2)Cya page
Mutation
origin
Strain of Origin:  C57BL/6JCya
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Mutation:    Insertion
 
Tmem119em1(cre/ERT2)Cya expression driven by 1 gene
    CRISPR/cas9-mediated recombination inserted a cre/ERT2 fusion gene into the stop codon (J:326541)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tmem119 (mouse)
Summary of all recombinase alleles driven by Tmem119.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tmem119 Mutation:  25 strains or lines available
References
Original:  J:372508 Jiang L, et al., Functional Monomers Equipped Microgel System for Managing Parkinson's Disease by Intervening Chemokine Axis-mediated Nerve Cell Communications. Adv Sci (Weinh). 2025 Feb;12(7):e2410070
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory