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Gt(ROSA)26Sorem1(CAG-dre)Ylu
Endonuclease-mediated Allele Detail
Summary
Symbol: Gt(ROSA)26Sorem1(CAG-dre)Ylu
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Youming Lu
MGI ID: MGI:8252959
Synonyms: C on /F off -DRE
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sorem1(CAG-dre)Ylu page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Conditional ready, Recombinase)
Mutation:    Insertion
 
Gt(ROSA)26Sorem1(CAG-dre)Ylu expression driven by 1 gene
 
Mutation detailsA pCAG-LoxP-STOP-LoxP-FRT-DRE-FRT-WPRE-pA construct was inserted in the gene. Expression of dre is turned on by cre-mediated removal of the STOP sequence. Flp-mediated removal the the dre sequence will turn off dre expression. (J:350514)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: CAG (chicken)
Summary of all recombinase alleles driven by CAG.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  1060 strains or lines available
References
Original:  J:350514 Li X, et al., Molecularly defined and functionally distinct cholinergic subnetworks. Neuron. 2022 Nov 16;110(22):3774-3788.e7
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory