Prdm13<em1(cre/ERT2)Saak> Endonuclease-mediated Allele Detail MGI Mouse (MGI:8250861)

Prdm13^{em1(cre/ERT2)Saak}
Endonuclease-mediated Allele Detail

Summary

Symbol:	Prdm13^{em1(cre/ERT2)Saak}
Name:	PR domain containing 13; endonuclease-mediated mutation 1, Akiko Satoh
MGI ID:	MGI:8250861
Synonyms:	Prdm13-CreERT2
Gene:	Prdm13 Location: Chr4:21677480-21685963 bp, - strand Genetic Position: Chr4, 8.78 cM
Alliance:	Prdm13^{em1(cre/ERT2)Saak} page

Mutation
origin

Strain of Origin:

C57BL/6J

Mutation
description

Allele Type:

Endonuclease-mediated (Recombinase)

Inducer:

tamoxifen

Mutation:

Insertion

Prdm13^{em1(cre/ERT2)Saak} expression driven by 1 gene

Mutation details: CRISPR/cas9-mC mediated recombination inserted a P2A-cre/ERT2-rabbit globin polyA cassette in place of the TAA stop codon in exon 4. (J:346891)

Inheritance:

Not Specified

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Prdm13 (mouse) Summary of all recombinase alleles driven by Prdm13. Alliance mouse Prdm13 gene page

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Prdm13 Mutation:	48 strains or lines available

References

Original:	J:346891 Tsuji S, et al., Sleep-wake patterns are altered with age, Prdm13 signaling in the DMH, and diet restriction in mice. Life Sci Alliance. 2023 Jun;6(6)
All:	1 reference(s)

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