Epx<em1(icre/ERT2)Wwz> Endonuclease-mediated Allele Detail MGI Mouse (MGI:8250846)

Epx^{em1(icre/ERT2)Wwz}
Endonuclease-mediated Allele Detail

Summary

Symbol:	Epx^{em1(icre/ERT2)Wwz}
Name:	eosinophil peroxidase; endonuclease-mediated mutation 1, Wenwen Zeng
MGI ID:	MGI:8250846
Synonyms:	Epx^iCreERT2
Gene:	Epx Location: Chr11:87754826-87766362 bp, - strand Genetic Position: Chr11, 52.25 cM
Alliance:	Epx^{em1(icre/ERT2)Wwz} page

Mutation
origin

Strain of Origin:

C57BL/6

Mutation
description

Allele Type:

Endonuclease-mediated (Inducible, Recombinase)

Inducer:

tamoxifen

Mutation:

Insertion

Epx^{em1(icre/ERT2)Wwz} expression driven by 1 gene

CRISPR/cas9-mediated recombination inserted a P2A-icre/ERT2 cassette before the stop codon. (J:351390)

Inheritance:

Not Specified

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Epx (mouse) Summary of all recombinase alleles driven by Epx. Alliance mouse Epx gene page

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Epx Mutation:	34 strains or lines available

References

Original:	J:351390 Meng X, et al., Eosinophils regulate intra-adipose axonal plasticity. Proc Natl Acad Sci U S A. 2022 Jan 18;119(3):e2112281119
All:	1 reference(s)

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