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Tas1r2tm1.1(cre)Kyr
Targeted Allele Detail
Summary
Symbol: Tas1r2tm1.1(cre)Kyr
Name: taste receptor, type 1, member 2; targeted mutation 1.1, George A Kyriazis
MGI ID: MGI:8250829
Synonyms: Tas1r2-Cre
Gene: Tas1r2  Location: Chr4:139380849-139397591 bp, + strand  Genetic Position: Chr4, 70.82 cM
Alliance: Tas1r2tm1.1(cre)Kyr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:347056
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Tas1r2tm1.1(cre)Kyr expression driven by 1 gene
 
Mutation details: A cre-pA cassette followed by an FRT-flanked neo cassette were inserted immediately downstream of the start site via homologous recombination. Flp-mediated recombination removed the neo cassette. (J:347056)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tas1r2 (mouse)
Summary of all recombinase alleles driven by Tas1r2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tas1r2 Mutation:  53 strains or lines available
References
Original:  J:347056 Serrano J, et al., Saccharin Stimulates Insulin Secretion Dependent on Sweet Taste Receptor-Induced Activation of PLC Signaling Axis. Biomedicines. 2022 Jan 6;10(1)
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/07/2025
MGI 6.24 		The Jackson Laboratory