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Sema6dtm1.1(cre)Akum
Targeted Allele Detail
Summary
Symbol: Sema6dtm1.1(cre)Akum
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D; targeted mutation 1.1, Atsushi Kumanogoh
MGI ID: MGI:8250813
Synonyms: Sema6dIRES-Cre
Gene: Sema6d  Location: Chr2:123931889-124509690 bp, + strand  Genetic Position: Chr2, 60.69 cM
Alliance: Sema6dtm1.1(cre)Akum page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:353779
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Sema6dtm1.1(cre)Akum expression driven by 1 gene
 
Mutation details: An IRES-cre cassette and floxed neo cassette were inserted at the end of the coding region in exon 17 upstream of the 3' UTR via homologous recombination. Cre-mediated recombination removed the neo cassette. (J:353779)
Inheritance:    Not Specified
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Sema6d (mouse)
Summary of all recombinase alleles driven by Sema6d.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sema6d Mutation:  62 strains or lines available
Notes
Lentiviral gene trap injected into zygotes.
References
Original:  J:353779 Nakanishi Y, et al., Semaphorin 6D tunes amygdalar circuits for emotional, metabolic, and inflammatory outputs. Neuron. 2024 Sep 4;112(17):2955-2972.e9
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/07/2025
MGI 6.24 		The Jackson Laboratory