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Prox1em1(cre)Rssr
Endonuclease-mediated Allele Detail
Summary
Symbol: Prox1em1(cre)Rssr
Name: prospero homeobox 1; endonuclease-mediated mutation 1, R Sathish Srinivasan
MGI ID: MGI:8250580
Synonyms: Prox1-2A-Cre
Gene: Prox1  Location: Chr1:189850232-189902911 bp, - strand  Genetic Position: Chr1, 95.85 cM
Alliance: Prox1em1(cre)Rssr page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Prox1em1(cre)Rssr expression driven by 1 gene
    CRISPR/cas9-mediated recombination inserted a P2A-cre cassette in exon 6 at the TAG stop codon. (J:363177)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Prox1 (mouse)
Summary of all recombinase alleles driven by Prox1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prox1 Mutation:  50 strains or lines available
References
Original:  J:363177 Ho YC, et al., PROX1 Inhibits PDGF-B Expression to Prevent Myxomatous Degeneration of Heart Valves. Circ Res. 2023 Sep;133(6):463-480
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory