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Gpr45em3(cre/ERT2)Mjkr
Endonuclease-mediated Allele Detail
Summary
Symbol: Gpr45em3(cre/ERT2)Mjkr
Name: G protein-coupled receptor 45; endonuclease-mediated mutation 3, Michael J Krashes
MGI ID: MGI:8250559
Synonyms: Gpr45-CreERT2
Gene: Gpr45  Location: Chr1:42992032-43074611 bp, + strand  Genetic Position: Chr1, 21.88 cM, cytoband C1
Alliance: Gpr45em3(cre/ERT2)Mjkr page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Gpr45em3(cre/ERT2)Mjkr expression driven by 1 gene
    CRISPR/cas9-mediated recombination inserted a T2A-creERT2 cassette at the stop codon. (J:370121)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gpr45 (mouse)
Summary of all recombinase alleles driven by Gpr45.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gpr45 Mutation:  26 strains or lines available
References
Original:  J:370121 Karolczak EO, et al., Uncovering the role of Gpr45 in obesity regulation. Mol Metab. 2025 May 29;98:102174
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory