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Lyve1em1(cre/ERT2)Fgnx
Endonuclease-mediated Allele Detail
Summary
Symbol: Lyve1em1(cre/ERT2)Fgnx
Name: lymphatic vessel endothelial hyaluronan receptor 1; endonuclease-mediated mutation 1, Florent Ginhoux
MGI ID: MGI:8250489
Synonyms: Lyve1CreERT2
Gene: Lyve1  Location: Chr7:110449814-110462160 bp, - strand  Genetic Position: Chr7, 57.89 cM, cytoband F2
Alliance: Lyve1em1(cre/ERT2)Fgnx page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Mutation:    Insertion
 
Lyve1em1(cre/ERT2)Fgnx expression driven by 1 gene
 
Mutation details: CRISPR/cas9-mediated recombination inserted an IRES-cre/ERT2 cassette 63 bp downstream of the translation stop codon. (J:372130)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Lyve1 (mouse)
Summary of all recombinase alleles driven by Lyve1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lyve1 Mutation:  17 strains or lines available
References
Original:  J:372130 Yu X, et al., Septal LYVE1(+) macrophages control adipocyte stem cell adipogenic potential. Science. 2025 Aug 28;389(6763):eadg1128
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
10/07/2025
MGI 6.24 		The Jackson Laboratory