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Spibem2(cre/ERT2)Smue
Endonuclease-mediated Allele Detail
Summary
Symbol: Spibem2(cre/ERT2)Smue
Name: Spi-B transcription factor (Spi-1/PU.1 related); endonuclease-mediated mutation 2, Scott N Mueller
MGI ID: MGI:8250394
Synonyms: SpiBT2A-tdTomato
Gene: Spib  Location: Chr7:44175417-44181495 bp, - strand  Genetic Position: Chr7, 28.83 cM
Alliance: Spibem2(cre/ERT2)Smue page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase, Reporter)
Inducer:    tamoxifen
Mutation:    Insertion
 
Spibem2(cre/ERT2)Smue expression driven by 1 gene
    CRISPR-targeting inserted T2A-reporter-IRES-Cre/ERT2CRE after the last codon exon. (J:335283)
Inheritance:    Not Specified
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Spib (mouse)
Summary of all recombinase alleles driven by Spib.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Spib Mutation:  23 strains or lines available
References
Original:  J:335283 Alexandre YO, et al., A diverse fibroblastic stromal cell landscape in the spleen directs tissue homeostasis and immunity. Sci Immunol. 2022 Jan 7;7(67):eabj0641
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory