Pmp2<em1(cre/ERT2)Jmi> Endonuclease-mediated Allele Detail MGI Mouse (MGI:8249314)

Pmp2^{em1(cre/ERT2)Jmi}
Endonuclease-mediated Allele Detail

Summary

Symbol:	Pmp2^{em1(cre/ERT2)Jmi}
Name:	peripheral myelin protein 2; endonuclease-mediated mutation 1, Jeffrey Milbrandt
MGI ID:	MGI:8249314
Synonyms:	Pmp2-Cre^ERT2
Gene:	Pmp2 Location: Chr3:10244911-10248945 bp, - strand Genetic Position: Chr3, 2.54 cM
Alliance:	Pmp2^{em1(cre/ERT2)Jmi} page

Mutation
origin

Strain of Origin:

Not Specified

Mutation
description

Allele Type:

Endonuclease-mediated (Inducible, Recombinase)

Inducer:

tamoxifen

Mutation:

Insertion

Pmp2^{em1(cre/ERT2)Jmi} expression driven by 1 gene

Mutation details: A tamoxifen-inducible Cre cassette (CreERT2) was inserted following the ATG codon of the target gene. (J:372541)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pmp2 (mouse) Summary of all recombinase alleles driven by Pmp2. Alliance mouse Pmp2 gene page

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Pmp2 Mutation:	11 strains or lines available

References

Original:	J:372541 Kozlowski MM, et al., Pmp2+ Schwann Cells Maintain the Survival of Large-Caliber Motor Axons. J Neurosci. 2025 Mar 26;45(13)
All:	1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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