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Pax9em1(cre/ERT2)Crxu
Endonuclease-mediated Allele Detail
Summary
Symbol: Pax9em1(cre/ERT2)Crxu
Name: paired box 6; endonuclease-mediated mutation 1, Cheng-Ran Xu
MGI ID: MGI:8249295
Synonyms: Pax9-CreERT2-EGFP
Gene: Pax6  Location: Chr2:105499245-105527709 bp, + strand  Genetic Position: Chr2, 55.31 cM
Alliance: Pax9em1(cre/ERT2)Crxu page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, No functional change, Recombinase, Reporter)
Inducer:    tamoxifen
Mutation:    Insertion
 
Pax9em1(cre/ERT2)Crxu expression driven by 1 gene
 
Mutation details: CRISPR/Cas9 genome editing technology was used to insert a P2A-CreERT2-P2A-EGFP sequence before the translation stop codon of the target gene. (J:361676)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pax9 (mouse)
Summary of all recombinase alleles driven by Pax9.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pax6 Mutation:  92 strains or lines available
References
Original:  J:361676 Li KR, et al., Spatiotemporal and genetic cell lineage tracing of endodermal organogenesis at single-cell resolution. Cell. 2025 Feb 6;188(3):796-813.e24
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
10/07/2025
MGI 6.24 		The Jackson Laboratory