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Fosem1(icre/ERT2)Phsh
Endonuclease-mediated Allele Detail
Summary
Symbol: Fosem1(icre/ERT2)Phsh
Name: FBJ osteosarcoma oncogene; endonuclease-mediated mutation 1, Minoru Narita
MGI ID: MGI:8244919
Synonyms: Fostm1(icreERT2)Phsh
Gene: Fos  Location: Chr12:85520664-85524047 bp, + strand  Genetic Position: Chr12, 39.7 cM
Alliance: Fosem1(icre/ERT2)Phsh page
Mutation
origin
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Fosem1(icre/ERT2)Phsh expression driven by 1 gene
 
Mutation detailsCRISPR/Cas9 genome editing technology was used to replace the TGA stop codon with a P2A-iCreERT2 cassette. (J:352897)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Fos (mouse)
Summary of all recombinase alleles driven by Fos.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fos Mutation:  43 strains or lines available
References
Original:  J:352897 Katsuda Y, et al., Histone modification of pain-related gene expression in spinal cord neurons under a persistent postsurgical pain-like state by electrocautery. Mol Brain. 2021 Sep 20;14(1):146
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/30/2025
MGI 6.24
The Jackson Laboratory