About   Help   FAQ
Terttm1.1(cre/ERT2)JPark
Targeted Allele Detail
Summary
Symbol: Terttm1.1(cre/ERT2)JPark
Name: telomerase reverse transcriptase; targeted mutation 1.1, Jae-II Park
MGI ID: MGI:8244782
Synonyms: TERTTCE
Gene: Tert  Location: Chr13:73775030-73797962 bp, + strand  Genetic Position: Chr13, 40.12 cM
Alliance: Terttm1.1(cre/ERT2)JPark page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:236835
Parent Cell Line:  G4 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6NCrl)F1
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase, Reporter)
Mutation:    Insertion
 
Terttm1.1(cre/ERT2)JPark expression driven by 1 gene
 
Mutation details: A TCE cassette, consisting of a tdTomato reporter, a tamoxifen-inducible cre/ERT2 gene and a frt-flanked neomycin selection cassete, was inserted in-frame into exon 1 of the gene. The neomycin selection cassette was removed via FLP-mediated recombination. (J:236835)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tert (mouse)
Summary of all recombinase alleles driven by Tert.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tert Mutation:  54 strains or lines available
References
Original:  J:236835 Jun S, et al., LIG4 mediates Wnt signalling-induced radioresistance. Nat Commun. 2016 Mar 24;7:10994
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory