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Atf5tm1(cre)Stlo
Targeted Allele Detail
Summary
Symbol: Atf5tm1(cre)Stlo
Name: activating transcription factor 5; targeted mutation 1, Stavros Lomvardas
MGI ID: MGI:8238883
Synonyms: Atf5(rep)
Gene: Atf5  Location: Chr7:44461680-44466082 bp, - strand  Genetic Position: Chr7, 28.92 cM
Alliance: Atf5tm1(cre)Stlo page
Mutation
origin
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Recombinase, Reporter)
Mutation:    Insertion
 
Atf5tm1(cre)Stlo expression driven by 1 gene
 
Mutation details: The targeting construct replaced the entire coding sequence (CDS) with an iRFP713-p2a-Cre cassette; introduced a FRT-Neo-FRT positive selection cassette into a non-conserved region roughly 300nt downstream of the annotated 3UTR; and introduced a DTA negative selection cassette downstream of the 3 homology arm. (J:349562)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Atf5 (mouse)
Summary of all recombinase alleles driven by Atf5.
 

Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Atf5 Mutation:  22 strains or lines available
References
Original:  J:349562 Shayya HJ, et al., ER stress transforms random olfactory receptor choice into axon targeting precision. Cell. 2022 Oct 13;185(21):3896-3912.e22
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
08/05/2025
MGI 6.24 		The Jackson Laboratory