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Trem2em4(cre/ERT2)Cya
Endonuclease-mediated Allele Detail
Summary
Symbol: Trem2em4(cre/ERT2)Cya
Name: triggering receptor expressed on myeloid cells 2; endonuclease-mediated mutation 4, Cyagen Biosciences
MGI ID: MGI:8235727
Synonyms: Trem2em4(IRES-CreERT2)
Gene: Trem2  Location: Chr17:48653429-48659304 bp, + strand  Genetic Position: Chr17, 23.99 cM, cytoband C
Alliance: Trem2em4(cre/ERT2)Cya page
Mutation
origin
Strain of Origin:  C57BL/6JCya
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Trem2em4(cre/ERT2)Cya expression driven by 1 gene
 
Mutation details: The IRES-CreERT2 cassette was inserted 40 to 60 bp downstream of the TGA stop codon. CreERT2 recombinase is expressed under the regulatory control of the endogenous gene elements. (J:326541)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Trem2 (mouse)
Summary of all recombinase alleles driven by Trem2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Trem2 Mutation:  64 strains or lines available
References
Original:  J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
07/29/2025
MGI 6.24 		The Jackson Laboratory