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Tph2em2(cre/ERT2)Cya
Endonuclease-mediated Allele Detail
Summary
Symbol: Tph2em2(cre/ERT2)Cya
Name: tryptophan hydroxylase 2; endonuclease-mediated mutation 2, Cyagen Biosciences
MGI ID: MGI:8235724
Synonyms: Tph2em1(P2A-CreERT2)
Gene: Tph2  Location: Chr10:114914546-115020927 bp, - strand  Genetic Position: Chr10, 63.51 cM
Alliance: Tph2em2(cre/ERT2)Cya page
Mutation
origin
Strain of Origin:  C57BL/6JCya
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tph2em2(cre/ERT2)Cya expression driven by 1 gene
 
Mutation details: The allele was generated via genome editing by replacing the TGA stop codon of the mouse gene with a P2A-CreERT2 cassette. (J:326541)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tph2 (mouse)
Summary of all recombinase alleles driven by Tph2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tph2 Mutation:  43 strains or lines available
References
Original:  J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
07/29/2025
MGI 6.24 		The Jackson Laboratory