Gfi1em1(cre/ERT2)Cya
Endonuclease-mediated Allele Detail
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| Symbol: |
Gfi1em1(cre/ERT2)Cya |
| Name: |
growth factor independent 1 transcription repressor; endonuclease-mediated mutation 1, Cyagen Biosciences |
| MGI ID: |
MGI:8235575 |
| Synonyms: |
Gfi1em1(P2A-EGFP-CreERT2) |
| Gene: |
Gfi1 Location: Chr5:107864521-107873671 bp, - strand Genetic Position: Chr5, 52.23 cM
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| Alliance: |
Gfi1em1(cre/ERT2)Cya page
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| Allele Type: |
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Endonuclease-mediated (Inducible, Recombinase, Reporter) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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Gfi1em1(cre/ERT2)Cya expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: The TGA stop codon was replaced with the P2A-EGFP-CreERT2 cassette. CreERT2 recombinase and enhanced green fluorescent protein (EGFP) are expressed under the regulatory control of the endogenous gene elements. This model is a Tamoxifen-inducible Cre mouse, and when crossed with allele containing loxP sites, the offspring allele are expected to undergo sequence recombination between loxP sites mediated by Cre recombinase in Gfi1-positive cells following Tamoxifen induction. In addition to studies of Cre recombinase-mediated gene recombination, this model can also be used for EGFP fluorescent protein tracing studies.
(J:326541)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Gfi1
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Gfi1 Mutation: |
32 strains or lines available
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Analysis Tools
