Gene Expression Data
Assay Details
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Assay
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Reference:
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J:256001
Jung EM, et al., Arid1b haploinsufficiency disrupts cortical interneuron development and mouse behavior. Nat Neurosci. 2017 Dec;20(12):1694-1707
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:8227947
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Gene symbol:
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Dlg4
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Gene name:
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discs large MAGUK scaffold protein 4
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Results
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Specimen
S9a Arid1b+/+ VGluT1:
postnatal day 91
(more  )
Specimen
S9a Arid1b+/+ VGluT1:
(close  )
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Genetic Background:
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C57BL/6N
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Age:
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postnatal day 91
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cerebral cortex |
Present |
Punctate |
S9a Arid1b+/+ Merge
,
S9a Arid1b+/+ PSD95
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Expression was detected in excitatory synaptic puncta in the cortex.
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Specimen
S9a Arid1b+/- VGluT1:
(close )
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Genetic Background:
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B6(C)-Arid1btm1b(EUCOMM)Hmgu
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Mutant Allele(s):
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Arid1btm1b(EUCOMM)Hmgu/Arid1b+
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Age:
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postnatal day 91
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cerebral cortex |
Present |
Punctate |
S9a Arid1b+/- Merge
,
S9a Arid1b+/- PSD95
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No changes were observed in the number of excitatory synapses assessed by colocalized puncta of the postsynaptic marker Dlg4 (PSD95) and presynaptic marker Slc17a7 (VGluT1) in P91 Arid1b+/- cortices.
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Analysis Tools
